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News and Events

COVID-19 Virus Can Cause Inflammation in Infected Placentas

COVID-19 Virus Can Cause Inflammation in Infected Placentas

SARS-CoV-2 infections of women in late pregnancy frequently spread to their placentas and led to inflammation, according to a study from investigators at Weill Cornell Medicine and NewYork-Presbyterian. The findings suggest that further research is needed on the virus’s effects in pregnancy and underscore the current recommendation by the U.S. Centers for Disease Control and Prevention that pregnant women continue to take precautions, such as masking, social distancing and vaccination, to...

Advance in Understanding Cell Division Could Lead to New Cancer Treatments

Advance in Understanding Cell Division Could Lead to New Cancer Treatments

A protein called CDC7, long thought to play an essential role early in the cell division process, is in fact replaceable by another protein called CDK1, according to a study by investigators at Weill Cornell Medicine and the Dana-Farber Cancer Institute. The finding represents a fundamental advance in cell biology and may lead to new cancer therapies, since cancers frequently alter the molecular machinery of cell division to sustain their rapid growth.

The...

Are COVID-19-Linked Arrhythmias Caused by Viral Damage to the Heart’s Pacemaker Cells?

Are COVID-19-Linked Arrhythmias Caused by Viral Damage to the Heart’s Pacemaker Cells?

The SARS-CoV-2 virus can infect specialized pacemaker cells that maintain the heart’s rhythmic beat, setting off a self-destruction process within the cells, according to a preclinical study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and NYU Grossman School of Medicine. The findings offer a possible explanation for the heart arrhythmias that are commonly observed in patients with SARS-CoV-2 infection.

In the...

A Potential New Target for Cancer Immunotherapies

A Potential New Target for Cancer Immunotherapies

Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments, according to a study from researchers at Weill Cornell Medicine and Albert Einstein College of Medicine.

In the study, published Mar. 16 in Science Translational Medicine, the researchers found strong evidence that ART1, when...

Pre-Clinical Model May Enable Development of New Treatments for Leading Cause of Age-Related Vision Loss

Pre-Clinical Model May Enable Development of New Treatments for Leading Cause of Age-Related Vision Loss

Researchers at Weill Cornell Medicine have developed a pre-clinical model of the leading cause of central vision loss in older individuals, called dry age-related macular degeneration (dry AMD), and used it to identify new treatment modalities and drug targets.

Previously created mouse models have not sufficiently mimicked the characteristics of dry AMD in humans. By contrast, the new model, described in a...

Brain Drain: Scientists Explain Why Neurons Consume So Much Fuel Even When at Rest

Brain Drain: Scientists Explain Why Neurons Consume So Much Fuel Even When at Rest

Pound for pound, the brain consumes vastly more energy than other organs, and, puzzlingly, it remains a fuel-guzzler even when its neurons are not firing signals called neurotransmitters to each other. Now researchers at Weill Cornell Medicine have found that the process of packaging neurotransmitters may be responsible for this energy drain.

In their study, reported Dec. 3 in Science Advances, they identified tiny...

New Technique Allows Scientists to See Proteins Moving as They Work

New Technique Allows Scientists to See Proteins Moving as They Work

Researchers at Weill Cornell Medicine have shown that they can record the high-speed motions of proteins while correlating their motion to function. The feat should allow scientists to study proteins in greater detail than ever before, and in principle enables the development of drugs that work better by hitting their protein targets much more effectively.

The researchers, in a study published July 16 in Nature...

Elegant Solution: Endocrinology Chief Dr. Laura Alonso—A Specialist in Diabetes Research and Treatment—is Exploring Ways to Restore the Body’s Insulin Production

Elegant Solution: Endocrinology Chief Dr. Laura Alonso—A Specialist in Diabetes Research and Treatment—is Exploring Ways to Restore the Body’s Insulin Production

The daughter of two nuclear physicists, Dr. Laura Alonso, was drawn to medicine while earning her undergrad degree in biochemistry from Harvard. She attended the University of Pennsylvania’s Perelman School of Medicine, followed by an internal medicine residency at the University of Chicago and fellowships in endocrinology and metabolism there and at New York University. Last September, she became chief of the Division of Endocrinology, Diabetes, and Metabolism at Weill Cornell Medicine...

Overcoming the Odds: Dr. Bishoy Faltas Works to Develop More Effective Therapies for Bladder Cancer

Overcoming the Odds: Dr. Bishoy Faltas Works to Develop More Effective Therapies for Bladder Cancer

By Emily Smith

Each year, 80,000 people in the United States are newly diagnosed with bladder cancer, and more than 17,000 lose their lives due to the disease. It ranks as the fourth most common type of cancer in men—but for decades, there was a paucity of research and little understanding of its unique biology, leaving clinicians with limited treatment options.

Dr. Bishoy Faltas, is changing that. An assistant professor of...

Pluripotent Stem Cells Shed Light on How COVID-19 Infects the Pancreas and Liver and Its Relationship with Diabetes

Pluripotent Stem Cells Shed Light on How COVID-19 Infects the Pancreas and Liver and Its Relationship with Diabetes

The study of human pluripotent stem cells, which can develop into any cell type in the body, is providing Weill Cornell Medicine and NewYork-Presbyterian investigators with new insights into the virus that causes COVID-19 and how it may infect organs such as the pancreas and liver.

The study, published June 19 in Cell Stem Cell, demonstrates that the severe acute...

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