Xin-Yun Huang, Ph.D.

The Huang Laboratory deciphers the structural biochemistry of membrane-spanning signaling proteins—particularly seven-transmembrane GPCRs and single-pass receptors—to reveal the molecular logic of cross-membrane communication. Additionally, we engineer small-molecule fascin inhibitors that arrest tumor metastasis and invigorate intratumoral dendritic cells, opening new frontiers in precision cancer therapy.