![Frederick Maxfield, Ph.D.](https://biochem.weill.cornell.edu/sites/default/files/styles/headshot/public/fred_maxfield.jpg?itok=sGmlPXlj)
Professor of Biochemistry
Phone:
(646) 962-2759
Email:
Research Area :
Affiliated Graduate Program :
![The current model of signaling required for the extracellular digestion of aggregated LDL (exophagy) is illustrated. This is a major focus of research in the Maxfield laboratory. Extracellular digestion of aggregated LDL illustration.](https://biochem.weill.cornell.edu/sites/default/files/profile_feature_images/maxfield-figure-1.jpg)
The Maxfield laboratory studies basic cell biology of membrane traffic and its application to understanding and treating diseases. Current interests include cholesterol transport, control of lysosomal pH and extracellular degradation of large objects (e.g., amyloid, dead adipocytes, or deposits of lipoproteins) by macrophages. These studies are related to atherosclerosis, Alzheimer’s disease and a rare lysosomal storage disease (Niemann-Pick C disease).
Lab Members
![](https://biochem.weill.cornell.edu/sites/default/files/styles/profile/public/default_images/profile.png?itok=wXtV211v)
Lucy Funes
Research Technician
![](https://biochem.weill.cornell.edu/sites/default/files/styles/profile/public/default_images/profile.png?itok=wXtV211v)
Jonathan Ma
Postdoctoral Associate
![](https://biochem.weill.cornell.edu/sites/default/files/styles/profile/public/default_images/profile.png?itok=wXtV211v)
Santiago Solé-Domenech
Assistant Professor of Research
![](https://biochem.weill.cornell.edu/sites/default/files/styles/profile/public/default_images/profile.png?itok=wXtV211v)
Noah Steinfeld
Postdoctoral Associate
![](https://biochem.weill.cornell.edu/sites/default/files/styles/profile/public/default_images/profile.png?itok=wXtV211v)
Alvin Wang
Research Technician