The Dephoure laboratory uses quantitative proteomics to globally monitor protein composition, abundance and post-translational modifications. The lab is trying to understand how signaling events such as phosphorylation regulate protein dynamics. The lab is also developing methods for identifying phosphorylation dependent changes in protein complex composition and protein subcellular localization. The hope is to leverage these methods to identify functional phosphorylation sites that impact cellular physiology and human disease.
Assistant Professor of Biochemistry Proteomics Core Director
Research Area :Molecular & Cellular Basis of Disease